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Exome-wide association study of plasma lipids in > 300,000 individuals
Liu, Dajiang J.; Peloso, Gina M.; Yu, Haojie; Butterworth, Adam S.; Wang, Xiao; Mahajan, Anubha; Saleheen, Danish; Emdin, Connor; Alam, Dewan; Alves, Alexessander Couto; Amouyel, Philippe; Di Angelantonio, Emanuele; Arveiler, Dominique; Assimes, Themistocles L.; Auer, Paul L.; Baber, Usman; Ballantyne, Christie M.; Bang, Lia E.; Benn, Marianne; Bis, Joshua C.; Boehnke, Michael; Boerwinkle, Eric; Bork-Jensen, Jette; Bottinger, Erwin P.; Brandslund, Ivan; Brown, Morris; Busonero, Fabio; Caulfield, Mark J.; Chambers, John C.; Chasman, Daniel I.; Chen, Y. Eugene; Chen, Yii-Der Ida; Chowdhury, Rajiv; Christensen, Cramer; Chu, Audrey Y.; Connell, John M.; Cucca, Francesco; Cupples, L. Adrienne; Damrauer, Scott M.; Davies, Gail; Deary, Ian J.; Dedoussis, George; Denny, Joshua C.; Dominiczak, Anna; Dube, Marie-Pierre; Ebeling, Tapani; Eiriksdottir, Gudny; Esko, Tonu; Farmaki, Aliki-Eleni; Feitosa, Mary F.; Ferrario, Marco; Ferrieres, Jean; Ford, Ian; Fornage, Myriam; Franks, Paul W.; Frayling, Timothy M.; Frikke-Schmidt, Ruth; Fritsche, Lars G.; Frossard, Philippe; Fuster, Valentin; Ganesh, Santhi K.; Gao, Wei; Garcia, Melissa E.; Gieger, Christian; Giulianini, Franco; Goodarzi, Mark O.; Grallert, Harald; Grarup, Niels; Groop, Leif; Grove, Megan L.; Gudnason, Vilmundur; Hansen, Torben; Harris, Tamara B.; Hayward, Caroline; Hirschhorn, Joel N.; Holmen, Oddgeir L.; Huffman, Jennifer; Huo, Yong; Hveem, Kristian; Jabeen, Sehrish; Jackson, Anne U.; Jakobsdottir, Johanna; Jarvelin, Marjo-Riitta; Jensen, Gorm B.; Jorgensen, Marit E.; Jukema, J. Wouter; Justesen, Johanne M.; Kamstrup, Pia R.; Kanoni, Stavroula; Karpe, Fredrik; Kee, Frank; Khera, Amit V.; Klarin, Derek; Koistinen, Heikki A.; Kooner, Jaspal S.; Kooperberg, Charles; Kuulasmaa, Kari; Kuusisto, Johanna; Laakso, Markku; Lakka, Timo; Langenberg, Claudia; Langsted, Anne; Launer, Lenore J.; Lauritzen, Torsten; Liewald, David C. M.; Lin, Li An; Linneberg, Allan; Loos, Ruth J. F.; Lu, Yingchang; Lu, Xiangfeng; Magi, Reedik; Malarstig, Anders; Manichaikul, Ani; Manning, Alisa K.; Mantyselka, Pekka; Marouli, Eirini; Masca, Nicholas G. D.; Maschio, Andrea; Meigs, James B.; Melander, Olle; Metspalu, Andres; Morris, Andrew P.; Morrison, Alanna C.; Mulas, Antonella; Mueller-Nurasyid, Martina; Munroe, Patricia B.; Neville, Matt J.; Nielsen, Jonas B.; Nielsen, Sune F.; Nordestgaard, Borge G.; Ordovas, Jose M.; Mehran, Roxana; O'Donnell, Christoper J.; Orho-Melander, Marju; Molony, Cliona M.; Muntendam, Pieter; Padmanabhan, Sandosh; Palmer, Colin N. A.; Pasko, Dorota; Patel, Aniruddh P.; Pedersen, Oluf; Perola, Markus; Peters, Annette; Pisinger, Charlotta; Pistis, Giorgio; Polasek, Ozren; Poulter, Neil; Psaty, Bruce M.; Rader, Daniel J.; Rasheed, Asif; Rauramaa, Rainer; Reilly, Dermot F.; Reiner, Alex P.; Renstrom, Frida; Rich, Stephen S.; Ridker, Paul M.; Rioux, John D.; Robertson, Neil R.; Roden, Dan M.; Rotter, Jerome I.; Rudan, Igor; Salomaa, Veikko; Samani, Nilesh J.; Sanna, Serena; Sattar, Naveed; Schmidt, Ellen M.; Scott, Robert A.; Sever, Peter; Sevilla, Raquel S.; Shaffer, Christian M.; Sim, Xueling; Sivapalaratnam, Suthesh; Small, Kerrin S.; Smith, Albert V.; Smith, Blair H.; Somayajula, Sangeetha; Southam, Lorraine; Spector, Timothy D.; Speliotes, Elizabeth K.; Starr, John M.; Stirrups, Kathleen E.; Stitziel, Nathan; Strauch, Konstantin; Stringham, Heather M.; Surendran, Praveen; Tada, Hayato; Tall, Alan R.; Tang, Hua; Tardif, Jean-Claude; Taylor, Kent D.; Trompet, Stella; Tsao, Philip S.; Tuomilehto, Jaakko; Tybjaerg-Hansen, Anne; van Zuydam, Natalie R.; Varbo, Anette; Varga, Tibor V.; Virtamo, Jarmo; Waldenberger, Melanie; Wang, Nan; Wareham, Nick J.; Warren, Helen R.; Weeke, Peter E.; Weinstock, Joshua; Wessel, Jennifer; Wilson, James G.; Wilson, Peter W. F.; Xu, Ming; Yaghootkar, Hanieh; Young, Robin; Zeggini, Eleftheria; Zhang, He; Zheng, Neil S.; Zhang, Weihua; Zhang, Yan; Zhou, Wei; Zhou, Yanhua; Zoledziewska, Magdalena; Howson, Joanna M. M.; Danesh, John; McCarthy, Mark I.; Cowan, Chad A.; Abecasis, Goncalo; Deloukas, Panos; Musunuru, Kiran; Willer, Cristen J.; Kathiresan, Sekar (2017)
An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans
Scott, Robert A.; Scott, Laura J.; Maegi, Reedik; Marullo, Letizia; Gaulton, Kyle J.; Kaakinen, Marika; Pervjakova, Natalia; Pers, Tune H.; Johnson, Andrew D.; Eicher, John D.; Jackson, Anne U.; Ferreira, Teresa; Lee, Yeji; Ma, Clement; Steinthorsdottir, Valgerdur; Thorleifsson, Gudmar; Qi, Lu; Van Zuydam, Natalie R.; Mahajan, Anubha; Chen, Han; Almgren, Peter; Voight, Ben F.; Grallert, Harald; Mueller-Nurasyid, Martina; Ried, Janina S.; Rayner, Nigel W.; Robertson, Neil; Karssen, Lennart C.; Van Leeuwen, Elisabeth M.; Willems, Sara M.; Fuchsberger, Christian; Kwan, Phoenix; Teslovich, Tanya M.; Chanda, Pritam; Li, Man; Lu, Yingchang; Dina, Christian; Thuillier, Dorothee; Yengo, Loic; Jiang, Longda; Sparso, Thomas; Kestler, Hans A.; Chheda, Himanshu; Eisele, Lewin; Gustafsson, Stefan; Franberg, Mattias; Strawbridge, Rona J.; Benediktsson, Rafn; Hreidarsson, Astradur B.; Kong, Augustine; Sigurdsson, Gunnar; Kerrison, Nicola D.; Luan, Jian'an; Liang, Liming; Meitinger, Thomas; Roden, Michael; Thorand, Barbara; Esko, Tonu; Mihailov, Evelin; Fox, Caroline; Liu, Ching-Ti; Rybin, Denis; Isomaa, Bo; Lyssenko, Valeriya; Tuomi, Tiinamaija; Couper, David J.; Pankow, James S.; Grarup, Niels; Have, Christian T.; Jorgensen, Marit E.; Jorgensen, Torben; Linneberg, Allan; Cornelis, Marilyn C.; Van Dam, Rob M.; Hunter, David J.; Kraft, Peter; Sun, Qi; Edkins, Sarah; Owen, Katharine R.; Perry, John R. B.; Wood, Andrew R.; Zeggini, Eleftheria; Tajes-Fernandes, Juan; Abecasis, Goncalo R.; Bonnycastle, Lori L.; Chines, Peter S.; Stringham, Heather M.; Koistinen, Heikki A.; Kinnunen, Leena; Sennblad, Bengt; Muehleisen, Thomas W.; Noethen, Markus M.; Pechlivanis, Sonali; Baldassarre, Damiano; Gertow, Karl; Humphries, Steve E.; Tremoli, Elena; Klopp, Norman; Meyer, Julia; Steinbach, Gerald; Wennauer, Roman; Eriksson, Johan G.; Mannisto, Satu; Peltonen, Leena; Tikkanen, Emmi; Charpentier, Guillaume; Eury, Elodie; Lobbens, Stephane; Gigante, Bruna; Leander, Karin; McLeod, Olga; Bottinger, Erwin P.; Gottesman, Omri; Ruderfer, Douglas; Blueher, Matthias; Kovacs, Peter; Tonjes, Anke; Maruthur, Nisa M.; Scapoli, Chiara; Erbel, Raimund; Joeckel, Karl-Heinz; Moebus, Susanne; De Faire, Ulf; Hamsten, Anders; Stumvoll, Michael; Deloukas, Panagiotis; Donnelly, Peter J.; Frayling, Timothy M.; Hattersley, Andrew T.; Ripatti, Samuli; Salomaa, Veikko; Pedersen, Nancy L.; Boehm, Bernhard O.; Bergman, Richard N.; Collins, Francis S.; Mohlke, Karen L.; Tuomilehto, Jaakko; Hansen, Torben; Pedersen, Oluf; Barroso, Ines; Lannfelt, Lars; Ingelsson, Erik; Lind, Lars; Lindgren, Cecilia M.; Cauchi, Stephane; Froguel, Philippe; Loos, Ruth J. F.; Balkau, Beverley; Boeing, Heiner; Franks, Paul W.; Gurrea, Aurelio Barricarte; Palli, Domenico; Van der Schouw, Yvonne T.; Altshuler, David; Groop, Leif C.; Langenberg, Claudia; Wareham, Nicholas J.; Sijbrands, Eric; Van Duijn, Cornelia M.; Florez, Jose C.; Meigs, James B.; Boerwinkle, Eric; Gieger, Christian; Strauch, Konstantin; Metspalu, Andres; Morris, Andrew D.; Palmer, Colin N. A.; Hu, Frank B.; Thorsteinsdottir, Unnur; Stefansson, Kari; Dupuis, Josee; Morris, Andrew P.; Boehnke, Michael; McCarthy, Mark I.; Prokopenko, Inga (2017)
Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass (Nature Communications 8:80)
Zillikens, M. Carola; Demissie, Serkalem; Hsu, Yi-Hsiang; Yerges-Armstrong, Laura M.; Chou, Wen-Chi; Stolk, Lisette; Livshits, Gregory; Broer, Linda; Johnson, Toby; Koller, Daniel L.; Kutalik, Zoltan; Luan, Jian'an; Malkin, Ida; Ried, Janina S.; Smith, Albert V.; Thorleifsson, Gudmar; Vandenput, Liesbeth; Zhao, Jing Hua; Zhang, Weihua; Aghdassi, Ali; Akesson, Kristina; Amin, Najaf; Baier, Leslie J.; Barroso, Ines; Bennett, David A.; Bertram, Lars; Biffar, Rainer; Bochud, Murielle; Boehnke, Michael; Borecki, Ingrid B.; Buchman, Aron S.; Byberg, Liisa; Campbell, Harry; Obanda, Natalia Campos; Cauley, Jane A.; Cawthon, Peggy M.; Cederberg, Henna; Chen, Zhao; Cho, Nam H.; Choi, Hyung Jin; Claussnitzer, Melina; Collins, Francis; Cummings, Steven R.; De Jager, Philip L.; Demuth, Ilja; Dhonukshe-Rutten, Rosalie A. M.; Diatchenko, Luda; Eiriksdottir, Gudny; Enneman, Anke W.; Erdos, Mike; Eriksson, Johan G.; Eriksson, Joel; Estrada, Karol; Evans, Daniel S.; Feitosa, Mary F.; Fu, Mao; Garcia, Melissa; Gieger, Christian; Girke, Thomas; Glazer, Nicole L.; Grallert, Harald; Grewal, Jagvir; Han, Bok-Ghee; Hanson, Robert L.; Hayward, Caroline; Hofman, Albert; Hoffman, Eric P.; Homuth, Georg; Hsueh, Wen-Chi; Hubal, Monica J.; Hubbard, Alan; Huffman, Kim M.; Husted, Lise B.; Illig, Thomas; Ingelsson, Erik; Ittermann, Till; Jansson, John-Olov; Jordan, Joanne M.; Jula, Antti; Karlsson, Magnus; Khaw, Kay-Tee; Kilpelanen, Tuomas O.; Klopp, Norman; Kloth, Jacqueline S. L.; Koistinen, Heikki A.; Kraus, William E.; Kritchevsky, Stephen; Kuulasmaa, Teemu; Kuusisto, Johanna; Laakso, Markku; Lahti, Jari; Lang, Thomas; Langdahl, Bente L.; Launer, Lenore J.; Lee, Jong-Young; Lerch, Markus M.; Lewis, Joshua R.; Lind, Lars; Lindgren, Cecilia; Liu, Yongmei; Liu, Tian; Liu, Youfang; Ljunggren, Osten; Lorentzon, Mattias; Luben, Robert N.; Maixner, William; McGuigan, Fiona E.; Medina-Gomez, Carolina; Meitinger, Thomas; Melhus, Hakan; Mellstrom, Dan; Melov, Simon; Michaelsson, Karl; Mitchell, Braxton D.; Morris, Andrew P.; Mosekilde, Leif; Newman, Anne; Nielson, Carrie M.; O'Connell, Jeffrey R.; Oostra, Ben A.; Orwoll, Eric S.; Palotie, Aarno; Parker, Stephen C. J.; Peacock, Munro; Perola, Markus; Peters, Annette; Polasek, Ozren; Prince, Richard L.; Raikkonen, Katri; Ralston, Stuart H.; Ripatti, Samuli; Robbins, John A.; Rotter, Jerome I.; Rudan, Igor; Salomaa, Veikko; Satterfield, Suzanne; Schadt, Eric E.; Schipf, Sabine; Scott, Laura; Sehmi, Joban; Shen, Jian; Shin, Chan Soo; Sigurdsson, Gunnar; Smith, Shad; Soranzo, Nicole; Stancakova, Alena; Steinhagen-Thiessen, Elisabeth; Streeten, Elizabeth A.; Styrkarsdottir, Unnur; Swart, Karin M. A.; Tan, Sian-Tsung; Tarnopolsky, Mark A.; Thompson, Patricia; Thomson, Cynthia A.; Thorsteinsdottir, Unnur; Tikkanen, Emmi; Tranah, Gregory J.; Tuomilehto, Jaakko; van Schoor, Natasja M.; Verma, Arjun; Vollenweider, Peter; Volzke, Henry; Wactawski-Wende, Jean; Walker, Mark; Weedon, Michael N.; Welch, Ryan; Wichmann, H. -Erich; Widen, Elisabeth; Williams, Frances M. K.; Wilson, James F.; Wright, Nicole C.; Xie, Weijia; Yu, Lei; Zhou, Yanhua; Chambers, John C.; Doring, Angela; van Duijn, Cornelia M.; Econs, Michael J.; Gudnason, Vilmundur; Kooner, Jaspal S.; Psaty, Bruce M.; Spector, Timothy D.; Stefansson, Kari; Rivadeneira, Fernando; Uitterlinden, Andre G.; Wareham, Nicholas J.; Ossowski, Vicky; Waterworth, Dawn; Loos, Ruth J. F.; Karasik, David; Harris, Tamara B.; Ohlsson, Claes; Kiel, Douglas P. (2017)
Preventive effects of multiple domain interventions on lifestyle and risk factor changes in stroke survivors: Evidence from a two-year randomized trial
Teuschl, Yvonne; Matz, Karl; Firlinger, Bernadette; Dachenhausen, Alexandra; Tuomilehto, Jaakko; Brainin, Michael (2017)
Effects of acarbose on cardiovascular and diabetes outcomes in patients with coronary heart disease and impaired glucose tolerance (ACE): a randomised, double-blind, placebo-controlled trial
Holman, Rury R.; Coleman, Roth L.; Chan, Juliana C. N.; Chiasson, Jean-Louis; Feng, Huimei; Ge, Junbo; Gerstein, Hertzel C.; Gray, Richard; Huo, Yong; Lang, Zhihui; McMurray, John; Ryden, Lars; Schroeder, Stefan; Sun, Yihong; Theodorakis, Michael J.; Tendera, Michal; Tucker, Lynne; Tuomilehto, Jaakko; Wei, Yidong; Yang, Wenying; Wang, Duolao; Hu, Dayi; Pan, Changyu (2017)
Termination of pregnancy and sterilisation in women with childhood-onset type 1 diabetes
Sjoberg, Lena; Kaaja, Risto; Gissler, Mika; Tuomilehto, Jaakko; Tiitinen, Aila; Pitkaniemi, Janne (2017)
Comparison of relationships between four common anthropometric measures and incident diabetes
Lee, Crystal Man Ying; Woodward, Mark; Pandeya, Nirmala; Adams, Robert; Barrett-Connor, Elizabeth; Boyko, Edward J.; Eliasson, Mats; Franco, Laercio J.; Fujimoto, Wilfred Y.; Gonzalez, Clicerio; Howard, Barbara V.; Jacobs, David R., Jr.; Keinanen-Kiukaanniemi, Sirkka; Magliano, Dianna; Schreiner, Pamela; Shaw, Jonathan E.; Stevens, June; Taylor, Anne; Tuomilehto, Jaakko; Wagenknecht, Lynne; Huxley, Rachel R. (2017)
Associations of CAIDE Dementia Risk Score with MRI, PIB-PET measures, and cognition
Stephen, Ruth; Liu, Yawu; Ngandu, Tiia; Rinne, Juha O.; Kemppainen, Nina; Parkkola, Riitta; Laatikainen, Tiina; Paajanen, Teemu; Hanninen, Tuomo; Strandberg, Timo; Antikainen, Riitta; Tuomilehto, Jaakko; Kiukaanniemi, Sirkka Keinanen; Vanninen, Ritva; Helisalmi, Seppo; Levalahti, Esko; Kivipelto, Miia; Soininen, Hilkka; Solomon, Alina (2017)
Evaluation of the modified FINDRISC to identify individuals at high risk for diabetes among middle-aged white and black ARIC study participants
Kulkarni, Manjusha; Foraker, Randi E.; McNeill, Ann M.; Girman, Cynthia; Golden, Sherita H.; Rosamond, Wayne D.; Duncan, Bruce; Schmidt, Maria Ines; Tuomilehto, Jaakko (2017)
The Prognostic Value of Fasting Plasma Glucose, Two-Hour Postload Glucose, and HbA(1c) in Patients With Coronary Artery Disease: A Report From EUROASPIRE IV: A Survey From the European Society of Cardiology
Shahim, Bahira; De Bacquer, Dirk; De Backer, Guy; Gyberg, Viveca; Kotseva, Kornelia; Mellbin, Linda; Schnell, Oliver; Tuomilehto, Jaakko; Wood, David; Ryden, Lars (2017)